University of Zagreb

School of Medicine

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MEF i FER zajedno u Erasmus Mundus združenom diplomskom studiju “NeuroData”

1. Prof.dr.sc.  Davor Ježek, doc. dr.sc. Alan Ivković: “BIOengineered grafts for Cartilage Healing In Patients” (BIO-CHIP) (Projekt je nastavak FP7 projekta BIOCOMET koji završava u studenom 2015. Spada u natječaj H2020-PHC-2015-single-stage_RTD, dakle to je suradni projekt istraživanja i razvoja. Koordinator je Sveučilište u Bazelu, ima 7 EU partnera. Uz MEF kao „povezane treće strane“ („linked third parties“) sudjeluju još tri institucije iz Hrvatske, PMF i VEF (Sveučilište u Zagrebu) te KB Sv. Duh te zajedno čine prema EK jednog partnera.)
2. Doc.dr.sc. Dinko Mitrečić: “Coordination Action in support of the sustainability and globalisation of the Joint Programming Initiative on Neurodegenerative Diseases” (JPsustaiND). (Koordinator je INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM). Radi se o natječaju H2020-HCO-2015, „Coordination and Support Action“, kojim se potiče umrežavanje i usavršavanje u području. Sudjeluje 15 EU partnera.)
3. Prof. dr.sc. Branka Bedenić: “Fast Assay for Pathogen Identification and Characterisation” (FAPIC) (Radi se o natječaju H2020-PHC-2014-two-stage, suradni projekt s 10 EU partnera)
4. Prof. dr.sc. Srećko Gajović i prof. dr.sc. Blanka Jergović: projekt potpore natječajima Europskog istraživačkog vijeća (ERC), za podizanje svijesti i informiranje javnosti o važnosti ovih prestižnih projekata. Pripada natječajima ERC-2014-SUPPORT-1, „Coordination and Support Action“ (ScienceSquared) (Koordinator je SCIENCE BUSINESS PUBLISHING LIMITED, a sudjeluje 8 partnera.)

1. Prof.dr.sc. Slobodan Vukićević – „Novel Bone Morphogenetic Protein-6 Biocompatible Carrier Device for Bone Regeneration“ – OSTEOGROW (Cooperation HEALTH, trajanje 2012-2016 ( 54 mjeseca))

1. Prof.dr.sc. Srećko Gajović (coordinator): „Glowbrain“ ili punim nazivom „Primjena matičnih stanica i biomaterijala u oporavku mozga – unapređivanje mogućnosti postojećeg istraživanja mozga kroz inovativno in vivo molekularno oslikavanje“
   Cilj ovog trogodišnjeg projekta je uvođenje najmodernije tehnologije koja će hrvatskim znanstvenicima omogućiti istraživanja matičnih stanica i njihovo praćenje u oporavku mozga našeg eksperimentalnog modela- miša. U projektu će uz istraživače iz Hrvatske sudjelovati i poznati znanstvenici iz sedam zemalja Europske Unije (Austrije, Češke, Italije, Mađarske, Njemačke, Portugala i Švedske) koji će svojim znanjem iz područja matičnih stanica, biomaterijala te snimanja mišjeg mozga pomoći hrvatskim znanstvenicima da se što uspješnije uključe u vodeća istraživanja u tom području. Glavni ciljevi projekta su modernizacija, inovacija i edukacija te informiranje šire javnosti o važnosti istraživanja novih pristupa liječenju bolesti mozga.

1. Prof.dr.sc. Nataša Jovanov Milošević: Brain Extracellular Matrix in Health and Disease (ECMNet)
2. Dr.sc. Mihaela Perić: Targeted chemotherapy towards diseases caused by endoparasites
3. Prof.dr.sc. Nataša Jovanov Milošević: European network on brain malformations (Neuro-MIG)

1. Prof.dr.sc. Ivo Barić: “European network and registry for homocysinurias and methylation defects” – E-HOD (15.2.2013 – 14.5.2016.)
2. Prof.dr.sc. Ivo Barić: “Inherited NeuRoMetabolic Diseases INFORMATION NETWORK“ InNerMeD-I-Network (1.4.2013 – 31.3.2016)

1. Prof. dr. Damir Nemet: “Clinical and biological factors determining severity and activity of chronic graft- versus-host disease after allogeneic hematopoietic stem cell transplantation”, (15.10.2013 – 15.10.2015), collaboration with National Cancer Institute, NIH (prof. dr. Živko Pavletić)

1. Prof.dr.sc. Fran Borovečki: “Post-translacijske modifikacije bjelančevina u patofiziologiji Parkinsove bolesti” (2014-2016)
2. Dr.sc. Kristina Mlinac: “Neuroplastin i gangliozidi u organizaciji sinaptičke membrane” (2014-2016)

1. Prof. dr.sc. Sven Seiwerth: „E-modules on HistoPathology: a valuable online tool for students, researchers and professionals – HIPON“, EACEA-LLP-KA3-ICT (Lifelong Learning Programme, European Commission), (1.1.2013 – 31.12.2015.)

1. Prof. Smilja Kalenić and Prof. Milica Katić- “The appropriateness of prescribing antibiotics in primary health care in Europe with respect to antibiotic resistance” (APRES). The APRES project aims at providing information and recommendations on the appropriateness of prescribing antibiotics in primary care. The appropriateness of prescribing antibiotics is the extent to which the pattern of prescribed antibiotics is congruent with the antibiotic resistance pattern of bacteria. Coordinator: STICHTING NEDERLANDS INSTITUUT VOOR ONDERZOEK VAN DE GEZONDHEIDSZORG, Nethrelands. UZSM- partner:  (1.10.2009 – 30.9.2013) http://www.nivel.nl/en/apres
2. Prof.dr.sc. Jadranka Mustajbegović Improving quality and safety in the hospital: The link between organisational culture, burnout and quality of care (ORCAB.)
   This is a multicentre study involving 10 partners from nine countries. The partners include universities from Greece, Ireland, United Kingdom (UK), Former Yugoslav Republic of Macedonia (FYROM), Croatia, Portugal, Turkey, Romania and Bulgaria. To date, relatively little systematic evidence exists as to what represents an effective and efficient way to improve quality of care and safety in hospitals and how hospital organisational culture influences quality and safety. The ORCAB project will address this gap. The overall aim of the ORCAB project is to benchmark the organisational factors that impact on health professionals well being, quality of hospital care and patient safety. It also aims at designing bottom-up interventions in order to improve patient safety and quality of hospital care. Coordinator: Aristotelio Panepistimio Thessalonikis, Greece. Cooperation HEALTH, duration 1.11.2009 – 30.4.2014. http://cordis.europa.eu/search/index.cfm?fuseaction=result.document&RS_LANG=FR&RS_RCN=13928635&q
3. Doc.dr.sc. Mislav Jelić- “Magnetic scaffolds for in vivo tissue engineering” (MAGISTER)
   MAGISTER is a frontier research project aiming to develop new conceptually type of Magnetic Scaffolds (MagS) for tissue regeneration and orthopaedic surgery. In MAGISTER the partnership comprises 20 partners from 11 European countries. It is coordinated by Consiglio Nazionale delle Ricerche (ceramic and magnetic nanostructured materials development and characterisation) ( 1.12.2008 – 30.11.2012) http://www.magister-project.eu/
4. Prof.dr.sc. Davor Ježek- “Bioreactor-based, clinically oriented manufacturing of engineered tissues” (BIO-COMET)Despite significant achievements in the field of regenerative medicine and the enormous potential for engineered tissue products, significant hurdles have prevented cellular therapies from gaining wide-spread clinical adoption. Manufacturing related issues have been proposed as key challenges to be addressed for the translation of regenerative therapies to the clinic and the successful commercialization of engineered products. Similar to other biotechnology sectors (e.g., vaccines or recombinant protein production), bioreactor systems could play a central role in establishing engineered tissues in the clinic. In fact, by automating and streamlining manufacturing processes, they would allow to improve product reproducibility, safety, standardization and possibly reach cost-effectiveness. This project aims at the development, pre-clinical and clinical testing of a sensor-based bioreactor system for the production of functional, autologous engineered grafts with reproducible properties. The bioreactor-based manufacturing paradigm will be addressed in the specific context of cartilage repair.(1.12.2011 – 30.11.2015)

COST Actions Project (B10, B21, B24, B27 i B35)

1. Prof.dr.sc. Srećko Gajović:  Vice Chair of COST Domain Committee „Biomedicine and Molecular Biosciences“ ( 2006 to 2011 )

BICRO – Proof of Concept

1. Prof.dr.sc. Slobodan Vukićević – „New technology for improving heart function after miocard infarction“

During our previous scientific research in humans we discovered the isoforms of morphogenetic protein1 and demonstrated the links with specific human pathological conditions, including acute miokard infarction. We showed the efficacy of targeted therapy on heart function improvement by applying polyclonal antibodies in adequate animal models. The goal of the project is to select the most efficacious combination of our new monoclonal antibodies raised against particular isoforms that improve the heart function after acute miokard infarction and to file a concept patent application protecting the core therapeutic mechanism as well as to protect intellectual property related to the structure of the therapeutic molecules used as treatment following miokard infarction. New mechanisms of disease progression, new therapeutic targets and new therapeutic interventions for the treatment of this major problem of modern medicine represent an innovation with global potential of commercial development. (01.10.2012.- 30.11.2013)

EAHC – SECOND PROGRAMME OF COMMUNITY ACTION IN THE FIELD OF HEALTH – 2008 – 2013 (DG SANCO)

1. Prof.dr.sc. Ivo Barić: „ European registry and network for Intoxication type Metabolic Diseases- E-IMD“ (01.01.2011- 31.12. 2013.)

Bilateral project, Croatian Austrian collaboration

1. Prof.dr.sc. Nada Čikeš: Plućna hipertenzija u sistemskoj sklerozi (2012-2014)

Bilateral project, Croatian Austrian collaboration

1. Prof.dr.sc. Srećko Gajović: “Regulacija prometa FGFR1 u tumorima mozga i živčanim matičnim stanicama” (2012-2014)

Bilateral project, Croatian Italian collaboration

1. Prof.dr.sc. Danka Grčević: „Role of PTX3 in osteoclast and osteoblast differentiation“

UKF- Unity Through  Knowledge Fund

1. Prof.dr.sc. Fran Borovečki : „ Location analysis of a-synuclein promoter binding in Parkinson’ disease“
2. Dr.sc. Petra Šimić: „ Bone morphogenetic protein-6 u osteoporozi“
3. Prof.dr.sc. Srećko Gajović: „ Regeneration and plasticity after ischemic brain damage studied on innovative transgenic mouse models“
4. Prof.dr.sc. Melita Šalković- Petrišić: „ Cytopathological characterization of the brain in a rat model of sporadic Alzheimer disease“ 15.6.2010 – 15.6.2012;
5. Prof.dr.sc. Slobodan Vukičević: „ Bone morphogenetic protein-1 isoforms in bone regeneration” (15.7.2010 – 15.7.2012)

Cogito

1. Prof.dr.sc. Kamelija Žarković: “Modifikacija elastina karbonilnim stresom: utjecaj na starenje i zadebljanje krvnih žila” (2013-2015)

Michael J. Fox (Parkinson)

1. Prof.dr.sc. Fran Borovečki: „ Deciphering the molecular effects of alfa- synuclein int he nucleus: DNA binding and transcriptional dysregulation“

IPA IIIc

1. Prof. dr.sc. Ivo Barić: Creation of research related infrastructure for Translational Medicine and Applied Genomics (2010 – 2012)

IPA IV

1. Prof.dr.sc. Jadranka Božikov: “Curriculum development for interdisciplinary postgraduate specialist study in Medical informatics” (19.08.2013.-18.02.2015.) MEDINFO

ADRIS

1. Prof.dr.sc. Lovorka Grgurević: HEPATOPROTECT- razvoj Nove terapije u liječenju jetrene ciroze (25.10.2013.-30.11.2014.)

HALMED

1. Prof.dr.sc. Vlasta Bradamante (doc.dr.sc. Nada Božina): Farmakogenomika i farmakovigilancija- sprečavanje nuspojava u individualizaciji terapije ( 02.2013-31.12,2013.)

DAAD

1. Prof.dr.sc. Srećko Gajović: “Geni koji kontroliraju kortikogenezu u oporavku i obnovi nakon ishemijske ozljede mišjeg mozga”